$1.8bn investment sees Lilly expand manufacturing footprint in Ireland

Eli Lilly and Company has announced a $1 billion expansion of its Limerick, Ireland, manufacturing site to increase production of biologic active ingredients, including those for its recently approved treatment for early symptomatic Alzheimer’s disease. The company also unveiled its new $800 million facility expansion in Kinsale, Ireland, which began making medicines last year to meet demand for Lilly’s latest diabetes and obesity treatments.

This additional investment is part of the most ambitious manufacturing expansion agenda in the company’s history. Since 2020, Lilly has committed more than $20 billion to build, expand and acquire manufacturing facilities in the U.S. and Europe.

“These investments will boost the production of some of our medicines, helping millions of people with diabetes, obesity and Alzheimer’s disease live the healthiest lives possible,” said Edgardo Hernandez, executive vice president and president of Lilly Manufacturing Operations. “We won’t stop there – these state-of-the-art facilities will also be equipped to support our promising pipeline molecules of the future.”

Once complete, Limerick will join Lilly’s global manufacturing network producing the biologic active ingredients for the company’s Alzheimer’s disease portfolio and other biologic medicines.

“Alzheimer’s disease is a devastating diagnosis for both the patient and for their loved ones, along with having a huge burden on society,” said Anne E. White, executive vice president and president of Lilly Neuroscience. “The treatments we will make here in Limerick offer the potential to be able to slow the progression of the disease and make life better for millions of people around the world.”

The announcement brings Lilly’s total Limerick investment to $2 billion, doubling the investment the company announced in March 2023. Advanced technologies such as machine learning, AI and automated robotics and systems at the site will enable right-first-time execution, all in support of the safe and reliable supply of medicines. As a part of this expansion, Lilly will create another 150 jobs for highly skilled workers in Limerick such as engineers, scientists, quality assurance professionals and operations personnel, for a total of 450 employees. Lilly initially announced the Limerick site in 2022 and broke ground in March 2023. Production of biologic active ingredients for Lilly medicines is on track to start in 2026.

The Limerick investment project is subject to planning approval, and the company will submit a planning application to the Limerick City and County Council in due course.

The Kinsale facility is pivotal to maintaining the safe and reliable supply of Lilly’s diabetes and obesity medications. The official opening of Lilly’s Kinsale manufacturing site expansion marks the completion of the state-of-the-art project to help meet the demand for current and future treatments. The site employs a digital-first process that integrates continuous manufacturing technology to create a new manufacturing platform for creating complex peptides. This facility was recently recognized as the winner of the Innovation category in the prestigious “Facility of the Year” awards program run by the International Society of Pharmaceutical Engineers.

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